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KMID : 0616120170480030208
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Korean Journal of Pharmacognosy
2017 Volume.48 No. 3 p.208 ~ p.212
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Antioxidative Activity and Active Compound Analysis of the Extract and Fractions of Corni Fructus
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Im Do-Youn
Lee Kyoung-In
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Abstract
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In this study, analysis of active compounds that are believed to be highly relevant to antioxidant activity was carried out on the methanol extract and its solvent fractions of Corni fructus. The DPPH radical scavenging activity for the comparison of antioxidant activity was higher in order of aqueous fraction > methanol extract > ethyl acetate fraction > n-hexane fraction. It is similar to the order of total polyphenol contents in the samples. As a result of LC-MS analysis, phenolic acid compounds such as caffeic acid, gallic acid and chlorogenic acid and lognin, which is known as a representative active ingredient of Corni fructus, were identified as active compounds. And the antioxidative activity and the total polyphenol content of the extracts and solvent fractions were found to be related to the contents of the compounds. Particularly, it was confirmed that phenolic acid such as caffeic acid contributes to the antioxidative activity of the aqueous fraction of Corni fructus methanol extract.
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KEYWORD
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Corni fructus , Antioxidative activity , Phenolic acid , Loganin , LC-MS
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